[Antibiotic therapy in periodontal disease. 1. Selection of antibiotics].
نویسندگان
چکیده
The purpose of this study was to evaluate antibiotics effective for periodontopathic bacteria as chemotherapeutic agents for periodontal diseases. Antimicrobial activities of ten agents were evaluated by determinating minimal inhibitory concentrations against six periodontopathic bacterial species ( Bacteroides gingivalis, B. melaninogenicus ss intermedius, Fusobacterium nucleatum, Eikenella corrodens, Actinobacillus actinomycetemcomitans, Capnocytophaga species) and by testing the susceptibilities to subgingival plaque bacteria. Among antimicrobial agents tested, Minocycline ( MINO) , Tetracycline (TC) , Penicillin G (PCG) , Cefmetazole, Clindamycin (CLDM) and Metronidazole (MD) revealed strong antimicrobial activities against black-pigmented Bacteroides. In addition, MINO was also more effective against other bacterial species tested. Against subgingival plaque
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عنوان ژورنال:
- Nihon Shishubyo Gakkai kaishi
دوره 29 2 شماره
صفحات -
تاریخ انتشار 1987